742 citations · 759 across the 3 of their papers we have counts for
3 papers
Meraculous-2D: Haplotype-sensitive Assembly of Highly Heterozygous genomes
Eugene Goltsman, Isaac Ho, Daniel Rokhsar
While many short read assemblers attempt to simplify the de Brujin graph by identifying and resolving variant-induced bubbles to produce a haploid mosaic result, this approach is o…
Meraculous2: fast accurate short-read assembly of large polymorphic genomes
Jarrod A. Chapman, Isaac Y. Ho, Eugene Goltsman +1
We present Meraculous2, an update to the Meraculous short-read assembler that includes (1) handling of allelic variation using "bubble" structures within the de Bruijn graph, (2) i…
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species
Keith R. Bradnam, Joseph N. Fass, Anton Alexandrov +88
Background - The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished g…