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q-bio.QM2026
SHREC: A Spectral Embedding-Based Approach for Ab-Initio Reconstruction of Helical Molecules
Guy Shapira, Yoel Shkolnisky
Cryo-electron microscopy (cryo-EM) has emerged as a powerful technique for determining the three-dimensional structures of biological molecules at near-atomic resolution. However,…
q-bio.QM2018
Common lines modeling for reference free ab-initio reconstruction in cryo-EM
Ido Greenberg, Yoel Shkolnisky
We consider the problem of estimating an unbiased and reference-free ab-inito model for non-symmetric molecules from images generated by single-particle cryo-electron microscopy. T…