9 papers
ASOCEM: Automatic Segmentation Of Contaminations in cryo-EM
Amitay Eldar, Ido Amos, Yoel Shkolnisky
Particle picking is currently a critical step in the cryo-electron microscopy single particle reconstruction pipeline. Contaminations in the acquired micrographs severely degrade t…
Super-resolution SAXS based on PSF engineering and sub-pixel detector translations
Benjamin Gutman, Michael Mrejen, Gil Shabat +3
Small-angle X-ray scattering (SAXS) technique enables convenient nanoscopic characterization for various systems and conditions. Nonetheless, lab-based SAXS systems intrinsically s…
KLT Picker: Particle Picking Using Data-Driven Optimal Templates
Amitay Eldar, Boris Landa, Yoel Shkolnisky
Particle picking is currently a critical step in the cryo-EM single particle reconstruction pipeline. Despite extensive work on this problem, for many data sets it is still challen…
Rank-one Multi-Reference Factor Analysis
Yariv Aizenbud, Boris Landa, Yoel Shkolnisky
In recent years, there is a growing need for processing methods aimed at extracting useful information from large datasets. In many cases the challenge is to discover a low-dimensi…
Multi-reference factor analysis: low-rank covariance estimation under unknown translations
Boris Landa, Yoel Shkolnisky
We consider the problem of estimating the covariance matrix of a random signal observed through unknown translations (modeled by cyclic shifts) and corrupted by noise. Solving this…
A common lines approach for ab-initio modeling of cyclically-symmetric molecules
Gabi Pragier, Yoel Shkolnisky
One of the challenges in single particle reconstruction in cryo-electron microscopy is to find a three-dimensional model of a molecule using its two-dimensional noisy projection-im…