88 citations · 319 across the 16 of their papers we have counts for
3 papers · 1 filter
Online control of the False Discovery Rate in group-sequential platform trials
Sonja Zehetmayer, Martin Posch, Franz Koenig
When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate (FDR) assume that…
On model-based time trend adjustments in platform trials with non-concurrent controls
Marta Bofill Roig, Pavla Krotka, Carl-Fredrik Burman +9
Platform trials can evaluate the efficacy of several treatments compared to a control. The number of treatments is not fixed, as arms may be added or removed as the trial progresse…
Optimal designs for the development of personalized treatment rules
David Azriel, Yosef Rinott, Martin Posch
We study the design of multi-armed parallel group clinical trials to estimate personalized treatment rules that identify the best treatment for a given patient with given covariate…