95 citations · 235 across the 11 of their papers we have counts for
11 papers
Lateral transport of domains in anionic lipid bilayer membranes under DC electric fields: A coarse-grained molecular dynamics study
Hiroaki Ito, Naofumi Shimokawa, Yuji Higuchi
Dynamic lateral transport of lipids, proteins, and self-assembled structures in biomembranes plays crucial roles in diverse cellular processes. In this study, we perform a coarse-g…
Three-phase coexistence in binary charged lipid membranes in hypotonic solution
Jingyu Guo, Hiroaki Ito, Yuji Higuchi +3
We investigated the phase separation of dioleoylphosphatidylserine (DOPS) and dipalmitoylphosphatidylcholine (DPPC) in giant unilamellar vesicles in hypotonic solution using fluore…
Coarse-grained molecular dynamics simulation for uptake of nanoparticles into a charged lipid vesicle dominated by electrostatic interactions
Naofumi Shimokawa, Hiroaki Ito, Yuji Higuchi
We use a coarse-grained molecular dynamics simulation to investigate the interaction between neutral or charged nanoparticles (NPs) and a vesicle consisting of neutral and negative…
Coarse-grained molecular dynamics simulation of binary charged lipid membranes: Phase separation and morphological dynamics
Hiroaki Ito, Yuji Higuchi, Naofumi Shimokawa
Biomembranes, which are mainly composed of neutral and charged lipids, exhibit a large variety of functional structures and dynamics. Here, we report a coarse-grained molecular dyn…
Nano-domain formation in charged membranes: Beyond Debye-Huckel approximation
Ryuichi Okamoto, Naofumi Shimokawa, Shigeyuki Komura
We investigate the microphase separation in a membrane composed of charged lipid, by taking into account explicitly the electrostatic potential and the ion densities in the surroun…
Phase diagrams and ordering in charged membranes: Binary mixtures of charged and neutral lipids
Naofumi Shimokawa, Hiroki Himeno, Tsutomu Hamada +3
We propose a model describing the phase behavior of two-component membranes consisting of binary mixtures of electrically charged and neutral lipids. We take into account the struc…
Coupling between pore formation and phase separation in charged lipid membranes
Hiroki Himeno, Hiroaki Ito, Yuji Higuchi +3
We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids. We observed the membran…
Charge-induced phase separation in lipid membranes
Hiroki Himeno, Naofumi Shimokawa, Shigeyuki Komura +3
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibi…
Charged bilayer membranes in asymmetric ionic solutions: Phase diagrams and critical behavior
N. Shimokawa, S. Komura, D. Andelman
We consider the phase separation in an asymmetrically charged lipid bilayer membrane consisting of neutral and negatively charged lipids that are in contact with in/out ionic solut…
The Phase Behavior of Mixed Lipid Membranes in Presence of the Rippled Phase
N. Shimokawa, S. Komura, D. Andelman
We propose a model describing liquid-solid phase coexistence in mixed lipid membranes by including explicitly the occurrence of a rippled phase. For a single component membrane, we…
Tension-Induced Morphological Transition in Mixed Lipid Bilayers
S. Komura, N. Shimokawa, D. Andelman
Recently, Rozovsky et al. reported on the morphology and dynamics of superstructures in three-component lipid bilayers containing saturated and unsaturated lipids as well as choles…