activity
20132019
most citedMulticellular rosettes drive fluid-solid transition in epithelial tissues

92 citations · 405 across the 14 of their papers we have counts for

collaborators

14 papers

cond-mat.soft2019

Competition between entropy and energy in network glass: the hidden connection between intermediate phase and liquid-liquid transition

J. Quetzalcoatl Toledo-Marin, Le Yan

In network glass including chalcogenides, the network topology of microscopic structures can be tuned by changing the chemical compositions. As the composition is varied, an interm…

physics.bio-ph2019★ 22 cited

Mechanics of allostery: contrasting the induced fit and population shift scenarios

Riccardo Ravasio, Solange Flatt, Le Yan +3

In allosteric proteins, binding a ligand can affect function at a distant location, for example by changing the binding affinity of a substrate at the active site. The induced fit…

q-bio.PE2018★ 2 cited

Phylodynamics of rapidly adapting pathogens: extinction and speciation of a Red Queen

Le Yan, Richard Neher, Boris I Shraiman

Rapidly evolving pathogens like influenza viruses can persist by accumulating antigenic novelty fast enough to evade the adaptive immunity of the host population, yet without conti…

physics.bio-ph2018★ 92 cited

Multicellular rosettes drive fluid-solid transition in epithelial tissues

Le Yan, Dapeng Bi

Models for confluent biological tissues often describe the network formed by cells as a triple-junction network, similar to foams. However, higher order vertices or multicellular r…

cond-mat.stat-mech2017★ 29 cited

Entropy favors heterogeneous structures of networks near the rigidity threshold

Le Yan

The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity of the interaction networks, whic…

physics.bio-ph2017★ 35 cited

Principles for optimal cooperativity in allosteric materials

Le Yan, Riccardo Ravasio, Carolina Brito +1

Allosteric proteins transmit a mechanical signal induced by binding a ligand. However, understanding the nature of the information transmitted and the architectures optimizing such…

cond-mat.soft2016★ 10 cited

Edge Mode Amplification in Disordered Elastic Networks

Le Yan, Jean-Philippe Bouchaud, Matthieu Wyart

We study theoretically and numerically the propagation of a displacement field imposed at the edge of a disordered elastic material. While some modes decay with some inverse penetr…

cond-mat.soft2016★ 24 cited

Scale-free channeling patterns near the onset of erosion of sheared granular beds

Pascale Aussillous, Zhenhai Zou, Élisabeth Guazzelli +2

Erosion shapes our landscape and occurs when a sufficient shear stress is exerted by a fluid on a sedimented layer. What controls erosion at a microscopic level remains debated, es…

cond-mat.dis-nn2016★ 21 cited

On the Dynamics of Glassy Systems

Le Yan

Glassy systems are disordered systems characterized by extremely slow dynamics. Examples are supercooled liquids, whose dynamics slow down under cooling. The specific pattern of sl…

cond-mat.soft2016★ 49 cited

On Variational Arguments for Vibrational Modes near Jamming

Le Yan, Eric DeGiuli, Matthieu Wyart

Amorphous solids tend to present an abundance of soft elastic modes, which diminish their transport properties, generate heterogeneities in their elastic response, and affect non-l…

cond-mat.soft2015★ 14 cited

A model for the erosion onset of a granular bed sheared by a viscous fluid

Le Yan, Antoine Barizien, Matthieu Wyart

We study theoretically the erosion threshold of a granular bed forced by a viscous fluid. We first introduce a novel model of interacting particles driven on a rough substrate. It…

cond-mat.stat-mech2015★ 30 cited

Dynamics and Correlations among Soft Excitations in Marginally Stable Glasses

Le Yan, Marco Baity-Jesi, M. Mueller +1

Marginal stability is the notion that stability is achieved, but only barely so. This property constrains the ensemble of configurations explored at low temperature in a variety of…

cond-mat.dis-nn2014★ 28 cited

Evolution of covalent networks under cooling: contrasting the rigidity window and jamming scenarios

Le Yan, Matthieu Wyart

We study the evolution of structural disorder under cooling in supercooled liquids, focusing on covalent networks. We introduce a model for the energy of networks that incorporates…

cond-mat.dis-nn2013★ 49 cited

Why glass elasticity affects the thermodynamics and fragility of super-cooled liquids

Le Yan, Gustavo Düring, Matthieu Wyart

Super-cooled liquids are characterized by their fragility: the slowing down of the dynamics under cooling is more sudden and the jump of specific heat at the glass transition is ge…