activity
20132019
most citedMulticellular rosettes drive fluid-solid transition in epithelial tissues

92 citations · 405 across the 14 of their papers we have counts for

collaborators

14 papers

cond-mat.soft2019

Competition between entropy and energy in network glass: the hidden connection between intermediate phase and liquid-liquid transition

J. Quetzalcoatl Toledo-Marin, Le Yan

In network glass including chalcogenides, the network topology of microscopic structures can be tuned by changing the chemical compositions. As the composition is varied, an interm…

physics.bio-ph2019★ 22 cited

Mechanics of allostery: contrasting the induced fit and population shift scenarios

Riccardo Ravasio, Solange Flatt, Le Yan +3

In allosteric proteins, binding a ligand can affect function at a distant location, for example by changing the binding affinity of a substrate at the active site. The induced fit…

q-bio.PE2018★ 2 cited

Phylodynamics of rapidly adapting pathogens: extinction and speciation of a Red Queen

Le Yan, Richard Neher, Boris I Shraiman

Rapidly evolving pathogens like influenza viruses can persist by accumulating antigenic novelty fast enough to evade the adaptive immunity of the host population, yet without conti…

physics.bio-ph2018★ 92 cited

Multicellular rosettes drive fluid-solid transition in epithelial tissues

Le Yan, Dapeng Bi

Models for confluent biological tissues often describe the network formed by cells as a triple-junction network, similar to foams. However, higher order vertices or multicellular r…

cond-mat.stat-mech2017★ 29 cited

Entropy favors heterogeneous structures of networks near the rigidity threshold

Le Yan

The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity of the interaction networks, whic…

physics.bio-ph2017★ 35 cited

Principles for optimal cooperativity in allosteric materials

Le Yan, Riccardo Ravasio, Carolina Brito +1

Allosteric proteins transmit a mechanical signal induced by binding a ligand. However, understanding the nature of the information transmitted and the architectures optimizing such…