64 citations · 183 across the 6 of their papers we have counts for
Showing 2017 · q-bio.MNShow all
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q-bio.MN2017★ 64 cited
Simplification of Markov chains with infinite state space and the mathematical theory of random gene expression bursts
Chen Jia
Here we develop an effective approach to simplify two-time-scale Markov chains with infinite state spaces by removal of states with fast leaving rates, which improves the simplific…
q-bio.MN2017★ 58 cited
Emergent Lévy behavior in single-cell stochastic gene expression
Chen Jia, Michael Q. Zhang, Hong Qian
Single-cell gene expression is inherently stochastic; its emergent behavior can be defined in terms of the chemical master equation describing the evolution of the mRNA and protein…
q-bio.MN2017
Stochastic fluctuations can reveal the feedback signs of gene regulatory networks at the single-molecule level
Chen Jia, Peng Xie, Min Chen +1
Understanding the relationship between spontaneous stochastic fluctuations and the topology of the underlying gene regulatory network is of fundamental importance for the study of…