activity
20132022
most citedSmall protein number effects in stochastic models of autoregulated bursty gene expression

73 citations · 372 across the 19 of their papers we have counts for

collaborators

19 papers

cond-mat.stat-mech2022

Large deviations and fluctuation theorems for cycle currents defined in the loop-erased and spanning tree manners: a comparative study

Yuhao Jiang, Bingjie Wu, Chen Jia

The cycle current is a crucial quantity in stochastic thermodynamics. The absolute and net cycle currents of a Markovian system can be defined in the loop-erased (LE) or spanning t…

math.PR2021

Moderate and maximal inequalities for diffusion processes and conformal martingales

Xian Chen, Yong Chen, Mumien Cheng +1

The maximal inequalities for martingales are one of the classical results in the theory of stochastic processes. Here we establish the sharp moderate maximal inequalities for…

q-bio.SC2020★ 73 cited

Small protein number effects in stochastic models of autoregulated bursty gene expression

Chen Jia, Ramon Grima

A stochastic model of autoregulated bursty gene expression by Kumar et al. [Phys. Rev. Lett. 113, 268105 (2014)] has been exactly solved in steady-state conditions under the implic…

q-bio.MN2019★ 4 cited

Kinetic foundation of the zero-inflated negative binomial model for single-cell RNA sequencing data

Chen Jia

Single-cell RNA sequencing data have complex features such as dropout events, over-dispersion, and high-magnitude outliers, resulting in complicated probability distributions of mR…

q-bio.MN2019★ 57 cited

Single-cell stochastic gene expression kinetics with coupled positive-plus-negative feedback

Chen Jia, Le Yi Wang, George G. Yin +1

Here we investigate single-cell stochastic gene expression kinetics in a minimal coupled gene circuit with positive-plus-negative feedback. A triphasic stochastic bifurcation upon…

q-bio.MN2019★ 7 cited

Exact power spectrum in a minimal hybrid model of stochastic gene expression oscillations

Chen Jia, Hong Qian, Michael Q. Zhang

Stochastic oscillations in individual cells are usually characterized by a non-monotonic power spectrum with an oscillatory autocorrelation function. Here we develop an analytical…