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q-bio.MN2020
Signaling activations through G-protein-coupled-receptor aggregations
Masaki Watabe, Hideaki Yoshimura, Satya N. V. Arjunan +2
Eukaryotic cells transmit extracellular signal information to cellular interiors through the formation of a ternary complex made up of a ligand (or agonist), G-protein, and G-prote…
q-bio.MN2019
Cooperativity transitions driven by higher-order oligomer formations in ligand-induced receptor dimerization
Masaki Watabe, Satya N. V. Arjunan, Wei Xiang Chew +2
While cooperativity in ligand-induced receptor dimerization has been linked with receptor-receptor couplings via minimal representations of physical observables, effects arising fr…