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q-bio.MN2025
Invariant non-equilibrium dynamics of transcriptional regulation optimize information flow
Benjamin Zoller, Alexis Bénichou, Thomas Gregor +1
Eukaryotic gene regulation is based on stochastic yet controlled promoter switching, during which genes transition between transcriptionally active and inactive states. Despite the…
q-bio.MN2021
Eukaryotic gene regulation at equilibrium, or non?
Benjamin Zoller, Thomas Gregor, Gašper Tkačik
Models of transcriptional regulation that assume equilibrium binding of transcription factors have been very successful at predicting gene expression from sequence in bacteria. How…
q-bio.MN2010★ 7 cited
From statistical mechanics to information theory: understanding biophysical information-processing systems
Gašper Tkačik
These are notes for a set of 7 two-hour lectures given at the 2010 Summer School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa, Japan. The emphasis is on u…