20 citations · 41 across the 9 of their papers we have counts for
3 papers · 1 filter
Nonlocal decoding of positional and correlational information during development
Alex Chen Yi Zhang, Pablo Mateu Hoyos, David Brückner +1
In many developmental systems, cells differentiate into a tissue by reading out morphogen concentration fields, a process fundamentally limited by noise. How much can the precision…
Marr's three levels for embryonic development: information, dynamical systems, gene networks
David B. Brückner, Gašper Tkačik
Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge au…
Deriving a genetic regulatory network from an optimization principle
Thomas R Sokolowski, Thomas Gregor, William Bialek +1
Many biological systems approach physical limits to their performance, motivating the idea that their behavior and underlying mechanisms could be determined by such optimality. Nev…