93 citations · 242 across the 17 of their papers we have counts for
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Mass conserved elementary kinetics is sufficient for the existence of a non-equilibrium steady state concentration
Ronan M. T. Fleming, Ines Thiele
Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equil…
Existence of Positive Steady States for Mass Conserving and Mass-Action Chemical Reaction Networks with a Single Terminal-Linkage Class
Santiago Akle, Onkar Dalal, Ronan M. T. Fleming +3
We establish that mass conserving single terminal-linkage networks of chemical reactions admit positive steady states regardless of network deficiency and the choice of reaction ra…
A variational principle for computing nonequilibrium fluxes and potentials in genome-scale biochemical networks
Ronan M. T. Fleming, Christopher M. Maes, Michael A. Saunders +2
We derive a convex optimization problem on a steady-state nonequilibrium network of biochemical reactions, with the property that energy conservation and the second law of thermody…