4 papers · 1 filter
Variational kinetics: elementary reaction kinetics via conic optimisation
Ronan M. T. Fleming, Ines Thiele
Genome-scale modelling methods primarily predict reaction fluxes, whereas established high throughput experimental technologies primarily measure molecular species concentrations.…
Characterisation of conserved and reacting moieties in chemical reaction networks
Hadjar Rahou, Hulda S. Haraldsdottir, Filippo Martinelli +2
A detailed understanding of biochemical networks at the molecular level is essential for studying complex cellular processes. In this paper, we provide a comprehensive description…
MetaboTools: A comprehensive toolbox for analysis of genome-scale metabolic models
Maike K. Aurich, Ronan M. T. Fleming, Ines Thiele
Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly generated to study biological questions. Our previous work revealed the potential of ana…
ReconMap: An interactive visualisation of human metabolism
Alberto Noronha, Anna Dröfn Danielsdóttir, Freyr Jóhannsson +8
A genome-scale reconstruction of human metabolism, Recon 2, is available but no interface exists to interactively visualise its content integrated with omics data and simulation re…