6 citations · 6 across the 2 of their papers we have counts for
3 papers · 1 filter
Computer-aided modelling of complex physical systems with BondGraphTools
Peter Cudmore, Peter J. Gawthrop, Michael Pan +1
BondGraphTools is a Python library for scripted modelling of complex multi-physics systems. In contrast to existing modelling solutions, BondGraphTools is based upon the well estab…
Physically-Plausible Modelling of Biomolecular Systems: A Simplified, Energy-Based Model of the Mitochondrial Electron Transport Chain
Peter J. Gawthrop, Peter Cudmore, Edmund J. Crampin
Systems biology and whole-cell modelling are demanding increasingly comprehensive mathematical models of cellular biochemistry. These models require the development of simplified m…
Ca2+ release via IP3 receptors shapes the cytosolic Ca2+ transient for hypertrophic signalling in ventricular cardiomyocytes
Hilary Hunt, Agne Tilunaite, Greg Bass +4
Calcium (Ca2+) plays a central role in mediating both contractile function and hypertrophic signalling in ventricular cardiomyocytes. L-type Ca2+ channels trigger release of Ca2+ f…