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cs.LG2025
When three experiments are better than two: Avoiding intractable correlated aleatoric uncertainty by leveraging a novel bias--variance tradeoff
Paul Scherer, Andreas Kirsch, Jake P. Taylor-King
Real-world experimental scenarios are characterized by the presence of heteroskedastic aleatoric uncertainty, and this uncertainty can be correlated in batched settings. The bias--…
cs.LG2025
No Foundations without Foundations -- Why semi-mechanistic models are essential for regulatory biology
Luka Kovačević, Thomas Gaudelet, James Opzoomer +5
Despite substantial efforts, deep learning has not yet delivered a transformative impact on elucidating regulatory biology, particularly in the realm of predicting gene expression…