494 citations · 2.3k across the 51 of their papers we have counts for
10 papers · 1 filter
Quadrupolar active stress induces exotic phases of defect motion in active nematics
Salik A. Sultan, Mehrana R. Nejad, Amin Doostmohammadi
A wide range of living and artificial active matter exists in close contact with substrates and under strong confinement, where in addition to dipolar active stresses, quadrupolar…
Filopodia rotate and coil by actively generating twist in their actin shaft
Natascha Leijnse, Younes Farhangi Barooji, Mohammad Reza Arastoo +9
Filopodia are actin-rich structures, present on the surface of practically every known eukaryotic cell. These structures play a pivotal role in specific cell-cell and cell-matrix i…
Mechanics of cell integration in vivo
Guilherme B. Ventura, Aboutaleb Amiri, Raghavan Thiagarajan +3
During embryonic development, regeneration and homeostasis, cells have to physically integrate into their target tissues, where they ultimately execute their function. Despite a si…
Activity-induced instabilities of brain organoids
Kristian Thijssen, Guido L. A. Kusters, Amin Doostmohammadi
We present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to e…
Physics of liquid crystals in cell biology
Amin Doostmohammadi, Benoit Ladoux
The last decade has witnessed a rapid growth in understanding of the pivotal roles of mechanical stresses and physical forces in cell biology. As a result an integrated view of cel…
Mechanical basis and topological routes to cell elimination
Siavash Monfared, Guruswami Ravichandran, Jose E. Andrade +1
Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identif…
Half-integer and full-integer topological defects in polar active matter: Emergence, crossover, and coexistence
Aboutaleb Amiri, Romain Mueller, Amin Doostmohammadi
The presence and significance of active topological defects is increasingly realised in diverse biological and biomimetic systems. We introduce a continuum model of polar active ma…
Wrinkle force microscopy: a new machine learning based approach to predict cell mechanics from images
Honghan Li, Daiki Matsunaga, Tsubasa S. Matsui +4
Combining experiments with artificial intelligence algorithms, we propose a new machine learning based approach to extract the cellular force distributions from the microscope imag…
Phase field models of active matter
Romain Mueller, Amin Doostmohammadi
We present an overview of phase field modeling of active matter systems as a tool for capturing various aspects of complex and active interfaces. We first describe how interfaces b…
Activity pulses induce spontaneous flow reversals in viscoelastic environments
Emmanuel L. C. VI M. Plan, Julia M. Yeomans, Amin Doostmohammadi
Complex interactions between cellular systems and their surrounding extracellular matrices are emerging as important mechanical regulators of cell functions such as proliferation,…