4 papers
A Continual Learning Approach for Cross-Domain White Blood Cell Classification
Ario Sadafi, Raheleh Salehi, Armin Gruber +4
Accurate classification of white blood cells in peripheral blood is essential for diagnosing hematological diseases. Due to constantly evolving clinical settings, data sources, and…
A Hybrid HMM Approach for the Dynamics of DNA Methylation
Charalampos Kyriakopoulos, Pascal Giehr, Alexander Lück +2
The understanding of mechanisms that control epigenetic changes is an important research area in modern functional biology. Epigenetic modifications such as DNA methylation are in…
A Stochastic Model for the Formation of Spatial Methylation Patterns
Alexander Lück, Pascal Giehr, Jörn Walter +1
DNA methylation is an epigenetic mechanism whose important role in development has been widely recognized. This epigenetic modification results in heritable changes in gene express…
H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data
Charalampos Kyriakopoulos, Pascal Giehr, Verena Wolf
Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-droxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital rol…