2 papers
q-bio.GN2017
A Stochastic Model for the Formation of Spatial Methylation Patterns
Alexander Lück, Pascal Giehr, Jörn Walter +1
DNA methylation is an epigenetic mechanism whose important role in development has been widely recognized. This epigenetic modification results in heritable changes in gene express…
q-bio.GN2016
H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data
Charalampos Kyriakopoulos, Pascal Giehr, Verena Wolf
Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-droxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital rol…