148 citations · 583 across the 36 of their papers we have counts for
3 papers · 1 filter
Adjusting for time-varying treatment switches in randomized clinical trials: the danger of extrapolation and how to avoid it
Hege Michiels, An Vandebosch, Stijn Vansteelandt
When choosing estimands and estimators in randomized clinical trials, caution is warranted as intercurrent events, such as - due to patients who switch treatment after disease prog…
On Estimation and Cross-validation of Dynamic Treatment Regimes with Competing Risks
Pawel Morzywolek, Johan Steen, Wim Van Biesen +2
The optimal moment to start renal replacement therapy in a patient with acute kidney injury (AKI) remains a challenging problem in intensive care nephrology. Multiple randomised co…
A novel approach for identifying and addressing case-mix heterogeneity in individual participant data meta-analysis
Tat-Thang Vo, Raphael Porcher, Anna Chaimani +1
Case-mix heterogeneity across studies complicates meta-analyses. As a result of this, treatments that are equally effective on patient subgroups may appear to have different effect…