262 citations · 397 across the 6 of their papers we have counts for
6 papers
Extreme antagonism arising from gene-environment interactions
Thomas P. Wytock, Manjing Zhan, Adrian Jinich +3
Antagonistic interactions in biological systems, which occur when one perturbation blunts the effect of another, are typically interpreted as evidence that the two perturbations im…
Experimental evolution of diverse Escherichia coli metabolic mutants identifies genetic loci for convergent adaptation of growth rate
Thomas P. Wytock, Aretha Fiebig, Jonathan W. Willett +4
Cell growth is determined by substrate availability and the cell's metabolic capacity to assimilate substrates into building blocks. Metabolic genes that determine growth rate may…
Bridging the time scales of single-cell and population dynamics
Farshid Jafarpour, Charles S. Wright, Herman Gudjonson +7
How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale…
Intergenerational continuity of cell shape dynamics in Caulobacter crescentus
Charles S. Wright, Shiladitya Banerjee, Srividya Iyer-Biswas +3
We investigate the intergenerational shape dynamics of single Caulobacter crescentus cells using a novel combination of imaging techniques and theoretical modeling. We determine th…
Scaling laws governing stochastic growth and division of single bacterial cells
Srividya Iyer-Biswas, Charles S. Wright, Jonathan T. Henry +7
Uncovering the quantitative laws that govern the growth and division of single cells remains a major challenge. Using a unique combination of technologies that yields unprecedented…
Phase resetting reveals network dynamics underlying a bacterial cell cycle
Yihan Lin, Ying Li, Sean Crosson +2
Genomic and proteomic methods yield networks of biological regulatory interactions but do not provide direct insight into how those interactions are organized into functional modul…