6 citations · 12 across the 15 of their papers we have counts for
3 papers · 1 filter
T-cell receptor specificity landscape revealed through de novo peptide design
Gian Marco Visani, Michael N. Pun, Anastasia A. Minervina +3
T-cells play a key role in adaptive immunity by mounting specific responses against diverse pathogens. An effective binding between T-cell receptors (TCRs) and pathogen-derived pep…
Variability in the local and global composition of human T-cell receptor repertoires during thymic development across cell types and individuals
Giulio Isacchini, Valentin Quiniou, Hélène Vantomme +6
The adaptive immune response relies on T cells that combine phenotypic specialization with diversity of T cell receptors (TCRs) to recognize a wide range of pathogens. TCRs are acq…
On generative models of T-cell receptor sequences
Giulio Isacchini, Zachary Sethna, Yuval Elhanati +3
T-cell receptors (TCR) are key proteins of the adaptive immune system, generated randomly in each individual, whose diversity underlies our ability to recognize infections and mali…