100 citations · 275 across the 25 of their papers we have counts for
5 papers · 1 filter
Design principles of the cytotoxic CD8+ T-cell response
Obinna A. Ukogu, Zachary Montague, Grégoire Altan-Bonnet +1
Cytotoxic T lymphocytes eliminate infected or malignant cells, safeguarding surrounding tissues. Although experimental and systems-immunology studies have cataloged many molecular…
Loop-Diffusion: an equivariant diffusion model for designing and scoring protein loops
Kevin Borisiak, Gian Marco Visani, Armita Nourmohammad
Predicting protein functional characteristics from structure remains a central problem in protein science, with broad implications from understanding the mechanisms of disease to d…
Learning the shape of protein micro-environments with a holographic convolutional neural network
Michael N. Pun, Andrew Ivanov, Quinn Bellamy +5
Proteins play a central role in biology from immune recognition to brain activity. While major advances in machine learning have improved our ability to predict protein structure f…
Risk-utility tradeoff shapes memory strategies for evolving patterns
Oskar H Schnaack, Luca Peliti, Armita Nourmohammad
Keeping a memory of evolving stimuli is ubiquitous in biology, an example of which is immune memory for evolving pathogens. However, learning and memory storage for dynamic pattern…
Learning and organization of memory for evolving patterns
Oskar H Schnaack, Luca Peliti, Armita Nourmohammad
Storing memory for molecular recognition is an efficient strategy for responding to external stimuli. Biological processes use different strategies to store memory. In the olfactor…