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math.OC2003
Optimal length and signal amplification in weakly activated signal transduction cascades
Madalena Chaves, Eduardo D. Sontag, Robert J. Dinerstein
Weakly activated signaling cascades can be modeled as linear systems. The input-to-output transfer function and the internal gain of a linear system, provide natural measures for t…
math.OC2000
State-estimators for chemical reaction networks of Feinberg-Horn-Jackson zero deficiency type
Madalena Chaves, Eduardo D. Sontag
One of the most interesting questions in control theory is that of constructing observers. Observers compute estimates of the internal states of a dynamical system, using data prov…