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20152021
most citedLimitations of Label-Free Sensors in Serum Based Molecular Diagnostics

4 citations · 10 across the 11 of their papers we have counts for

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Showing 2019Show all

6 papers · 1 filter

physics.bio-ph20191 cited

Theoretical Limit Of Concentration Sensing of Single Receptor Artificial Biosensors

Tuhin Chakrabortty, Manoj M Varma

Artificially engineered biosensors are highly inefficient in accurately measuring the concentration of biomarkers, particularly, during early diagnosis of diseases. On the other ha…

physics.med-ph2019

Error reduction in biosensors using secondary labeling

Tuhin Chakrabortty, Manoj M Varma

In this article, we derive the limit of detection for a two-step molecular recognition process and show that in-spite of all the recognition reactions being in equilibrium the over…

physics.med-ph2019

Fundamental Limitations in Biomarker Based Early Disease Diagnosis

Tuhin Chakrabortty, Chandra R. Murthy, Manoj Varma

Clinical biosensors with low detection limit hold significant promise in the early diagnosis of debilitating diseases. Recent progress in sensor development has led to the demonstr…

physics.app-ph20191 cited

Tracking-free Determination of Microparticle Motion from Image Variance

Harish Sasikumar, Manoj M. Varma

In this work, we use the standard deviation of image pixel intensity to analyse the speed, direction and surface-interaction of microparticles in fluid. First, we present an analyt…

physics.bio-ph2019

Active modulation of surfactant driven flow instabilities by swarming bacteria

Harshitha S. Kotian, Shalini Harkar, Shubham Joge +4

Models based on surfactant driven instabilities have been employed to describe pattern formation by swarming bacteria. However, by definition, such models cannot account for the ef…

physics.bio-ph2019

Tuning the torque-speed characteristics of bacterial flagellar motor to enhance the swimming speed

Praneet Prakash, Amith Z. Abdulla, Varsha Singh +1

In a classic paper, Edward Purcell analysed the dynamics of flagellated bacterial swimmers and derived a geometrical relationship which optimizes the propulsion efficiency. Experim…