134 citations · 456 across the 10 of their papers we have counts for
11 papers
Chromatin and cytoskeletal tethering determine nuclear morphology in progerin expressing cells
M. C. Lionetti, S. Bonfanti, M. R. Fumagalli +6
The nuclear morphology of eukaryotic cells is determined by the interplay between the lamina forming the nuclear skeleton, the chromatin inside the nucleus and the coupling with th…
Unjamming of active rotators
Linda Ravazzano, Maria Chiara Lionetti, Maria Rita Fumagalli +5
Active particle assemblies can exhibit a wide range of interesting dynamical phases depending on internal parameters such as density, adhesion strength or self-propulsion. Active s…
Protein driven lipid domain nucleation in biological membranes
Moritz Hoferer, Silvia Bonfanti, Alessandro Taloni +2
Lipid rafts are heterogeneous dynamic lipid domains of the cell membranes that are involved in several biological processes, like protein and lipids specific transport and signalin…
From jamming to collective cell migration through a boundary induced transition
Oleksandr Chepizhko, Maria Chiara Lionetti, Chiara Malinverno +3
Cell monolayers provide an interesting example of active matter, exhibiting a phase transition from a flowing to jammed state as they age. Here we report experiments and numerical…
Cholesterol impairment contributes to neuroserpin aggregation
Costanza Giampietro, Maria Chiara Lionetti, Giulio Costantini +3
Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer's and Parkinson's diseases, and Familial Encephalopa…
Bursts of activity in collective cell migration
Oleksandr Chepizhko, Costanza Giampietro, Eleonora Mastrapasqua +11
Dense monolayers of living cells display intriguing relaxation dynamics, reminiscent of soft and glassy materials close to the jamming transition, and migrate collectively when spa…
Deformation and fracture of echinoderm collagen networks
Markus Ovaska, Zsolt Bertalan, Amandine Miksic +8
Collagen networks provide the main structural component of most tissues and represent an important ingredient for bio-mimetic materials for bio-medical applications. Here we study…
Volume changes during active shape fluctuations in cells
Alessandro Taloni, Elena Kardash, Oguz Umut Salman +3
Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape variations do not involve significant volume fluctuations. He…
Growth and form of melanoma cell colonies
Massimiliano Maria Baraldi, Alexander A Alemi, James P Sethna +3
We study the statistical properties of melanoma cell colonies grown in vitro by analyzing the results of crystal violet assays at different concentrations of initial plated cells a…
CXCR6, a Newly Defined Biomarker of Tissue-Specific Stem Cell Asymmetric Self-Renewal, Identifies More Aggressive Human Melanoma Cancer Stem Cells
Rouzbeh Taghizadeh, Minsoo Noh, Yang Hoon Huh +8
Background: A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells. Recent in…
AQP1 Is Not Only a Water Channel: It Contributes to Cell Migration through Lin7/Beta-Catenin
Elena Monzani, Riccardo Bazzotti, Carla Perego +1
Background: AQP1 belongs to aquaporins family, water-specific, membrane-channel proteins expressed in diverse tissues. Recent papers showed that during angiogenesis, AQP1 is expres…