205 citations · 238 across the 5 of their papers we have counts for
4 papers · 1 filter
Physics Approaches to the Spatial Distribution of Immune Cells in Tumors
Clare C. Yu, Juliana C. Wortman, Ting-Fang He +12
The goal of immunotherapy is to enhance the ability of the immune system to kill cancer cells. Immunotherapy is more effective and, in general, the prognosis is better, when more i…
Biological Regulatory Networks are Minimally Frustrated
Shubham Tripathi, David A. Kessler, Herbert Levine
Characterization of the differences between biological and random networks can reveal the design principles that enable the robust realization of crucial biological functions inclu…
Mathematical Modeling of Plasticity and Heterogeneity in EMT
Shubham Tripathi, Jianhua Xing, Herbert Levine +1
Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated b…
Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response
Dongya Jia, Xuefei Li, Federico Bocci +5
Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often…