205 citations · 229 across the 8 of their papers we have counts for
3 papers · 1 filter
Theoretical and computational tools to model multistable gene regulatory networks
Federico Bocci, Dongya Jia, Qing Nie +2
The last decade has witnessed a surge of theoretical and computational models to describe the dynamics of complex gene regulatory networks, and how these interactions can give rise…
Decoding the mechanisms underlying cell-fate decision-making during stem cell differentiation by Random Circuit Perturbation
Bin Huang, Mingyang Lu, Madeline Galbraith +3
Stem cells can precisely and robustly undergo cellular differentiation and lineage commitment, referred to as stemness. However, how the gene network underlying stemness regulation…
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma
Fengdan Ye, Dongya Jia, Mingyang Lu +2
Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthes…