93 citations · 305 across the 23 of their papers we have counts for
4 papers · 2 filters
Stochastic Cubic Regularization for Fast Nonconvex Optimization
Nilesh Tripuraneni, Mitchell Stern, Chi Jin +2
This paper proposes a stochastic variant of a classic algorithm---the cubic-regularized Newton method [Nesterov and Polyak 2006]. The proposed algorithm efficiently escapes saddle…
A deep generative model for single-cell RNA sequencing with application to detecting differentially expressed genes
Romain Lopez, Jeffrey Regier, Michael Cole +2
We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent…
A deep generative model for gene expression profiles from single-cell RNA sequencing
Romain Lopez, Jeffrey Regier, Michael Cole +2
We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent…
Fast Black-box Variational Inference through Stochastic Trust-Region Optimization
Jeffrey Regier, Michael I. Jordan, Jon McAuliffe
We introduce TrustVI, a fast second-order algorithm for black-box variational inference based on trust-region optimization and the reparameterization trick. At each iteration, Trus…