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20152022
most citedA joint model of unpaired data from scRNA-seq and spatial transcriptomics for imputing missing gene expression measurements

59 citations · 140 across the 10 of their papers we have counts for

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8 papers · 1 filter

cs.LG20221 cited

Dynamic Survival Transformers for Causal Inference with Electronic Health Records

Prayag Chatha, Yixin Wang, Zhenke Wu +1

In medicine, researchers often seek to infer the effects of a given treatment on patients' outcomes. However, the standard methods for causal survival analysis make simplistic assu…

cs.LG201959 cited

A joint model of unpaired data from scRNA-seq and spatial transcriptomics for imputing missing gene expression measurements

Romain Lopez, Achille Nazaret, Maxime Langevin +4

Spatial studies of transcriptome provide biologists with gene expression maps of heterogeneous and complex tissues. However, most experimental protocols for spatial transcriptomics…

cs.LG2018

A Deep Generative Model for Semi-Supervised Classification with Noisy Labels

Maxime Langevin, Edouard Mehlman, Jeffrey Regier +3

Class labels are often imperfectly observed, due to mistakes and to genuine ambiguity among classes. We propose a new semi-supervised deep generative model that explicitly models n…

cs.LG2018

Information Constraints on Auto-Encoding Variational Bayes

Romain Lopez, Jeffrey Regier, Michael I. Jordan +1

Parameterizing the approximate posterior of a generative model with neural networks has become a common theme in recent machine learning research. While providing appealing flexibi…

cs.LG201746 cited

Stochastic Cubic Regularization for Fast Nonconvex Optimization

Nilesh Tripuraneni, Mitchell Stern, Chi Jin +2

This paper proposes a stochastic variant of a classic algorithm---the cubic-regularized Newton method [Nesterov and Polyak 2006]. The proposed algorithm efficiently escapes saddle…

cs.LG20176 cited

A deep generative model for single-cell RNA sequencing with application to detecting differentially expressed genes

Romain Lopez, Jeffrey Regier, Michael Cole +2

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent…