2 papers
q-bio.QM2020
Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots
Liam J. Ruske, Jochen Kursawe, Anestis Tsakiridis +4
The deluge of single-cell data obtained by sequencing, imaging and epigenetic markers has led to an increasingly detailed description of cell state. However, it remains challenging…
q-bio.TO2015
Multiscale modelling of intestinal crypt organization and carcinogenesis
Alexander G. Fletcher, Philip J. Murray, Philip K. Maini
Colorectal cancers are the third most common type of cancer. They originate from intestinal crypts, glands that descend from the intestinal lumen into the underlying connective tis…