49 citations · 69 across the 12 of their papers we have counts for
4 papers · 1 filter
Sensitivity of mRNA Translation
Gilad Poker, Michael Margaliot, Tamir Tuller
Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, exit, and elong…
Maximizing Protein Translation Rate in the Nonhomogeneous Ribosome Flow Model: A Convex Optimization Approach
Gilad Poker, Yoram Zarai, Michael Margaliot +1
Translation is an important stage in gene expression. During this stage, macro-molecules called ribosomes travel along the mRNA strand linking amino-acids together in a specific or…
Maximizing Protein Translation Rate in the Ribosome Flow Model: the Homogeneous Case
Yoram Zarai, Michael Margaliot, Tamir Tuller
Gene translation is the process in which intracellular macro-molecules, called ribosomes, decode genetic information in the mRNA chain into the corresponding proteins. Gene transla…
On Three Generalizations of Contraction
Eduardo D. Sontag, Michael Margaliot, Tamir Tuller
We introduce three forms of generalized contraction (GC). Roughly speaking, these are motivated by allowing contraction to take place after small transients in time and/or amplitud…