49 citations · 69 across the 12 of their papers we have counts for
3 papers · 1 filter
Variability in mRNA Translation: A Random Matrix Theory Approach
Michael Margaliot, Wasim Huleihel, Tamir Tuller
The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many "local" factors like the abundance…
Ribosome Flow Model with Extended Objects
Yoram Zarai, Michael Margaliot, Tamir Tuller
We study a deterministic mechanistic model for the flow of ribosomes along the mRNA molecule, called the ribosome flow model with extended objects (RFMEO). This model encapsulates…
A Deterministic Mathematical Model for Bidirectional Excluded Flow with Langmuir Kinetics
Yoram Zarai, Michael Margaliot, Tamir Tuller
In many important cellular processes, including mRNA translation, gene transcription, phosphotransfer, and intracellular transport, biological "particles" move along some kind of "…