57 citations · 336 across the 51 of their papers we have counts for
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Variability in mRNA Translation: A Random Matrix Theory Approach
Michael Margaliot, Wasim Huleihel, Tamir Tuller
The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many "local" factors like the abundance…
Optimal Translation Along a Circular mRNA
Yoram Zarai, Alexander Ovseevich, Michael Margaliot
The ribosome flow model on a ring (RFMR) is a deterministic model for translation of a circularized mRNA. We derive a new spectral representation for the optimal steady-state produ…
Ribosome Flow Model with Extended Objects
Yoram Zarai, Michael Margaliot, Tamir Tuller
We study a deterministic mechanistic model for the flow of ribosomes along the mRNA molecule, called the ribosome flow model with extended objects (RFMEO). This model encapsulates…
A Deterministic Model for One-Dimensional Excluded Flow with Local Interactions
Yoram Zarai, Michael Margaliot, Anatoly B. Kolomeisky
Natural phenomena frequently involve a very large number of interacting molecules moving in confined regions of space. Cellular transport by motor proteins is an example of such co…
A Deterministic Mathematical Model for Bidirectional Excluded Flow with Langmuir Kinetics
Yoram Zarai, Michael Margaliot, Tamir Tuller
In many important cellular processes, including mRNA translation, gene transcription, phosphotransfer, and intracellular transport, biological "particles" move along some kind of "…