204 citations · 265 across the 8 of their papers we have counts for
4 papers · 1 filter
Designing a single-molecule biophysics tool for characterizing DNA damage for techniques that kill infectious pathogens through DNA damage effects
Helen Miller, Adam J. M. Wollman, Mark C. Leake
Antibiotics such as the quinolones and fluoroquinolones kill bacterial pathogens ultimately through DNA damage. They target the essential type IIA topoisomerases in bacteria by sta…
Developing a new biophysical tool to combine magneto-optical tweezers with super-resolution fluorescence microscopy
Zhaokun Zhou, Helen Miller, Adam J. M. Wollman +1
We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse config…
Probing DNA interactions with proteins using a single-molecule toolbox: inside the cell, in a test tube, and in a computer
Adam J. M. Wollman, Helen Miller, Zhaokun Zhou +1
DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function.…
Superresolution imaging of single DNA molecules using stochastic photoblinking of minor groove and intercalating dyes
Helen Miller, Zhaokun Zhou, Adam J. M. Wollman +1
As proof-of-principle for generating superresolution structural information from DNA we applied a method of localization microscopy utilizing photoblinking comparing intercalating…