662 citations · 2.1k across the 22 of their papers we have counts for
23 papers
Diffusing diffusivity model with dichotomous noise
Dongho Lee, Jae-Hyung Jeon, Pascal Viot +1
We study Langevin dynamics with stochastic diffusivity arising from fluctuations of the surrounding medium. The diffusivity is modeled as Ornstein-Uhlenbeck process driven by symme…
Anomalous statistics in the Langevin equation with fluctuating diffusivity: from Brownian yet non-Gaussian diffusion to anomalous diffusion and ergodicity breaking
Takuma Akimoto, Jae-Hyung Jeon, Ralf Metzler +3
Diffusive motion is a fundamental transport mechanism in physical and biological systems, governing dynamics across a wide range of scales -- from molecular transport to animal for…
Fickian yet non-Gaussian diffusion in an annealed heterogeneous environment
Seongyu Park, Xavier Durang, Ralf Metzler +1
Fickian yet non-Gaussian diffusion is a ubiquitous phenomenon observed in various biological and soft matter systems. This anomalous dynamics is typically attributed to heterogeneo…
Viscoelastic active diffusion governed by nonequilibrium fractional Langevin equations: underdamped dynamics and ergodicity breaking
Sungmin Joo, Jae-Hyung Jeon
In this work, we investigate the active dynamics and ergodicity breaking of a nonequilibrium fractional Langevin equation (FLE) with a power-law memory kernel of the form $K(t)\sim…
Nonequilibrium diffusion of active particles bound to a semi-flexible polymer network: simulations and fractional Langevin equation
HyeongTark Han, Sungmin Joo, Takahiro Sakaue +1
In a viscoelastic environment, the diffusion of a particle becomes non-Markovian due to the memory effect. An open question is to quantitatively explain how self-propulsion particl…
Accessing power-law statistics under experimental constraints
Xavier Durang, Hyerim Ahn, Jae Youn Shim +2
Over the last decades, impressive progresses have been made in many experimental domains, e.g. microscopic techniques such as single-particle tracking, leading to plethoric amounts…
Active diffusion of self-propelled particles in flexible polymer networks
Yeongjin Kim, Sungmin Joo, Won Kyu Kim +1
Biopolymer networks having a meshwork topology, e.g., extracellular matrix and mucus gels, are ubiquitous. It is an open question to understand how self-propelled agents such as Ja…
Bayesian inference of scaled versus fractional Brownian motion
Samudrajit Thapa, Seongyu Park, Yeongjin Kim +3
We present a Bayesian inference scheme for scaled Brownian motion, and investigate its performance on synthetic data for parameter estimation and model selection in a combined infe…
Fractal and knot-free chromosomes facilitate nucleoplasmic transport
Yeonghoon Kim, Ludvig Lizana, Jae-Hyung Jeon
Chromosomes in the nucleus assemble into hierarchies of 3D domains that, during interphase, share essential features with a knot-free condensed polymer known as the fractal globule…
A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models
Seongyu Park, O-chul Lee, Xavier Durang +1
In the course of various biological processes, specific DNA-binding proteins must find a particular target sequence/protein or a damaged site on the DNA efficiently. DNA-binding pr…
Anomalous diffusion for active Brownian particles cross-linked to a networked polymer: Langevin dynamics simulation and theory
Sungmin Joo, Xavier Durang, O-chul Lee +1
Quantitatively understanding of the dynamics of an active Brownian particle (ABP) interacting with a viscoelastic polymer environment is a scientific challenge. It is intimately re…
Mapping the spectrum of 3D communities in human chromosome conformation capture data
Sang Hoon Lee, Yeonghoon Kim, Sungmin Lee +4
Several experiments show that the three dimensional (3D) organization of chromosomes affects genetic processes such as transcription and gene regulation. To better understand this…
Superdiffusion dominates intracellular particle motion in the supercrowded space of pathogenic Acanthamoeba castellanii
J. F. Reverey, J. -H. Jeon, H. Bao +3
Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules throu…
Scaled Brownian motion: a paradoxical process with a time dependent diffusivity for the description of anomalous diffusion
J. -H. Jeon, A. V. Chechkin, R. Metzler
Anomalous diffusion is frequently described by scaled Brownian motion (SBM), a Gaussian process with a power-law time dependent diffusion coefficient. Its mean squared displacement…
First passage behaviour of multi-dimensional fractional Brownian motion and application to reaction phenomena
Jae-Hyung Jeon, Aleksei V. Chechkin, Ralf Metzler
Fractional Brownian motion is a generalised Gaussian diffusive process that is found to describe numerous stochastic phenomena in physics and biology. Here we introduce a multi-dim…
Noisy continuous time random walks
Jae-Hyung Jeon, Eli Barkai, R. Metzler
Experimental studies of the diffusion of biomolecules in the environment of biological cells are routinely confronted with multiple sources of stochasticity, whose identification r…
Anomalous diffusion of phospholipids and cholesterols in a lipid bilayer and its origins
Jae-Hyung Jeon, Hector Martinez-Seara Monne, Matti Javanainen +1
Combining extensive molecular dynamics simulations of lipid bilayer systems of varying chemical composition with single-trajectory analyses we systematically elucidate the stochast…
Inequivalence of time and ensemble averages in ergodic systems: exponential versus power-law relaxation in confinement
Jae-Hyung Jeon, Ralf Metzler
Single particle tracking has become a standard tool to investigate diffusive properties, especially in small systems such as biological cells. Usually the resulting time series are…
First passage behaviour of fractional Brownian motion in two-dimensional wedge domains
J. -H. Jeon, A. V. Chechkin, R. Metzler
We study the survival probability and the corresponding first passage time density of fractional Brownian motion confined to a two-dimensional open wedge domain with absorbing boun…
Single particle tracking in systems showing anomalous diffusion: the role of weak ergodicity breaking
Stas Burov, Jae-Hyung Jeon, Ralf Metzler +1
Anomalous diffusion has been widely observed by single particle tracking microscopy in complex systems such as biological cells. The resulting time series are usually evaluated in…
In vivo anomalous diffusion and weak ergodicity breaking of lipid granules
Jae-Hyung Jeon, Vincent Tejedor, Stas Burov +5
Combining extensive single particle tracking microscopy data of endogenous lipid granules in living fission yeast cells with analytical results we show evidence for anomalous diffu…
How dsDNA breathing enhances its flexibility and instability on short length scales
O-chul Lee, Jae-Hyung Jeon, Wokyung Sung
We study the unexpected high flexibility of short dsDNA which recently has been reported by a number of experiments. Via the Langevin dynamics simulation of our Breathing DNA model…
Fractional Brownian motion and generalized Langevin equation motion in confined geometries
Jae-Hyung Jeon, Ralf Metzler
Motivated by subdiffusive motion of bio-molecules observed in living cells we study the stochastic properties of a non-Brownian particle whose motion is governed by either fraction…