150 citations · 385 across the 8 of their papers we have counts for
4 papers · 1 filter
DNA looping: the consequences and its control
Leonor Saiz, Jose M. G. Vilar
The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication. Here we…
Stochastic dynamics of macromolecular-assembly networks
Leonor Saiz, Jose M. G. Vilar
The formation and regulation of macromolecular complexes provides the backbone of most cellular processes, including gene regulation and signal transduction. The inherent complexit…
Multiprotein DNA looping
Jose M. G. Vilar, Leonor Saiz
DNA looping plays a fundamental role in a wide variety of biological processes, providing the backbone for long range interactions on DNA. Here we develop the first model for DNA l…
In vivo evidence of alternative loop geometries in DNA-protein complexes
Leonor Saiz, Jose M. G. Vilar
The in vivo free energy of looping double-stranded DNA by the lac repressor has a remarkable behavior whose origins are not fully understood. In addition to the intrinsic periodici…