birkhoff-hilbert contraction 1cooperative systems 1dimensionality reduction 1monotone systems 1projective metric 1
From the 1 of 3 linked papers with an AI index.
3 papers
eess.SY2026
Some intuition for why cooperative systems "look 1-dimensional" and 2-cooperative systems "look 2-dimensional"
Eduardo D. Sontag
The paper offers geometric intuition for why cooperative (monotone) systems behave like one-dimensional systems and two‑cooperative systems behave like two-dimensional systems, usi…
physics.bio-ph2026
Dynamics and dose response in scaffold ligand binding
Eduardo D. Sontag
This paper considers systems in which two or more ligands bind independently to a common scaffold. Such systems arise in a range of applications, including immunotherapy and synthe…
q-bio.QM2026
Dynamic response phenotypes and model discrimination in systems and synthetic biology
Eduardo D. Sontag
Biological systems encode function not primarily in steady states, but in the structure of transient responses elicited by time-varying stimuli. Overshoots, biphasic dynamics, adap…