439 citations · 2.2k across the 51 of their papers we have counts for
3 papers · 1 filter
Steric constraints in model proteins
Cristian Micheletti, Jayanth R. Banavar, Amos Maritan +1
A simple lattice model for proteins that allows for distinct sizes of the amino acids is presented. The model is found to lead to a significant number of conformations that are the…
Inverse design of proteins with hydrophobic and polar amino acids
C. Micheletti, F. Seno, A. Maritan +1
A two amino acid (hydrophobic and polar) scheme is used to perform the design on target conformations corresponding to the native states of twenty single chain proteins. Strikingly…
Protein design in a lattice model of hydrophobic and polar amino acids
C. Micheletti, F. Seno, A. Maritan +1
A general strategy is described for finding which amino acid sequences have native states in a desired conformation (inverse design). The approach is used to design sequences of 48…