activity
19982025
most citedGeometry and symmetry presculpt the free-energy landscape of proteins

225 citations · 1.3k across the 58 of their papers we have counts for

collaborators

58 papers

physics.bio-ph2025

Space-filling discrete helices

Jayanth R. Banavar, Achille Giacometti, Trinh X. Hoang +2

Proteins are linear chain molecules that play a central role in life and health. Protein native state folds are modular assemblies of space-filling building blocks of α-helices, \{…

cond-mat.soft2025★ 3 cited

The protein escape process at the ribosomal exit tunnel has conserved mechanisms across the domains of life

Phuong Thuy Bui, Trinh Xuan Hoang

The ribosomal exit tunnel is the primary structure affecting the release of nascent proteins at the ribosome. The ribosomal exit tunnels from different species have elements of con…

cond-mat.soft2025★ 2 cited

Energetic preference and topological constraint effects on the formation of DNA twisted toroidal bundles

Nhung T. T. Nguyen, Anh T. Ngo, Trinh X. Hoang

DNA toroids are compact torus-shaped bundles formed by one or multiple DNA molecules being condensed from the solution due to various condensing agents. It has been shown that the…

cond-mat.soft2025

Solvation enhances folding cooperativity and the topology dependence of folding rates in a lattice protein model

Nhung T. T. Nguyen, Pham Nam Phong, Duy Manh Le +2

The aqueous solvent profoundly influences protein folding, yet its effects are relatively poorly understood. In this study, we investigate the impact of solvation on the folding of…

cond-mat.soft2024

Amino acid characteristics in protein native state structures

Tatjana Škrbić, Achille Giacometti, Trinh X. Hoang +2

We present a geometrical analysis of the protrusion statistics of side chains in more than 4,000 high-resolution protein structures. We employ a coarse-grained representation of th…

cond-mat.soft2023

III. Geometrical framework for thinking about globular proteins: turns in proteins

Tatjana Škrbić, Achille Giacometti, Trinh X. Hoang +2

We have shown recently that the notion of poking pairwise interactions along a chain provides a unifying framework for understanding the formation of both secondary and the tertiar…