2 papers
stat.ME2022
Flexible evaluation of surrogacy in Bayesian adaptive platform studies
Michael C Sachs, Erin E Gabriel, Alessio Crippa +1
Trial level surrogates are useful tools for improving the speed and cost effectiveness of trials, but surrogates that have not been properly evaluated can cause misleading results.…
stat.ME2021
Sharp nonparametric bounds for decomposition effects with two binary mediators
Erin E Gabriel, Michael C Sachs, Arvid Sjölander
In randomized trials, once the total effect of the intervention has been estimated, it is often of interest to explore mechanistic effects through mediators along the causal pathwa…