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q-bio.PE2026
Inference of germinal center evolutionary dynamics via simulation-based deep learning
Duncan K Ralph, Athanasios G Bakis, Jared Galloway +6
B cells and the antibodies they produce are vital to health and survival, motivating research on the details of the mutational and evolutionary processes in the germinal centers (G…
q-bio.PE2024
Exact and efficient phylodynamic simulation from arbitrarily large populations
Michael Celentano, William S. DeWitt, Sebastian Prillo +1
Many biological studies involve inferring the evolutionary history of a sample of individuals from a large population and interpreting the reconstructed tree. Such an ascertained t…