239 citations · 3.6k across the 108 of their papers we have counts for
109 papers
Exclusion model of mRNA translation with collision-induced ribosome drop-off
Johannes Keisers, Joachim Krug
The translation of messenger RNA transcripts to proteins is commonly modeled as a one-dimensional totally asymmetric exclusion process with extended particles. Here we focus on the…
Branching with selection and mutation I: Mutant fitness of Fréchet type
Su-Chan Park, Joachim Krug, Léo Touzo +1
We investigate two stochastic models of a growing population subject to selection and mutation. In our models each individual carries a fitness which determines its mean offspring…
Unpredictable repeatability in molecular evolution
Suman G Das, Joachim Krug
The extent of parallel evolution at the genotypic level is quantitatively linked to the distribution of beneficial fitness effects (DBFE) of mutations. The standard view, based on…
Nonlinear dynamics of an epidemic compartment model with asymptomatic infections and mitigation
Maurice Görtz, Joachim Krug
A significant proportion of the infections driving the current {SARS-CoV-2} pandemic are transmitted asymptomatically. Here we introduce and study a simple epidemic model with sepa…
A Driven Disordered Systems Approach to Biological Evolution in Changing Environments
Suman G Das, Joachim Krug, Muhittin Mungan
Biological evolution of a population is governed by the fitness landscape, which is a map from genotype to fitness. However, a fitness landscape depends on the organisms environmen…
Geometry of fitness landscapes: Peaks, shapes and universal positive epistasis
Kristina Crona, Joachim Krug, Malvika Srivastava
Darwinian evolution is driven by random mutations, genetic recombination (gene shuffling) and selection that favors genotypes with high fitness. For systems where each genotype can…