3 papers
eess.SY2026
Control systems for synthetic biology and a case-study in cell fate reprogramming
Domitilla Del Vecchio
This paper gives an overview of the use of control systems engineering in synthetic biology, motivated by applications such as cell therapy and cell fate reprogramming for regenera…
math.DS2025
Contraction Dynamics in Heterogeneous Spatial Environments
Carlos Barajas, Jean-Jacques Slotine, Domitilla Del Vecchio
Understanding the asymptotic behavior of reaction-diffusion (RD) systems is crucial for modeling processes ranging from species coexistence in ecology to biochemical interactions w…
q-bio.MN2024
Competition for binding targets results in paradoxical effects for simultaneous activator and repressor action -- Extended Version
M. Ali Al-Radhawi, Krishna Manoj, Dhruv D. Jatkar +3
In the context of epigenetic transformations in cancer metastasis, a puzzling effect was recently discovered, in which the elimination (knock-out) of an activating regulatory eleme…