883 citations · 1k across the 3 of their papers we have counts for
3 papers
A single determinant for the rate of yeast protein evolution
D. Allan Drummond, Alpan Raval, Claus O. Wilke
A gene's rate of sequence evolution is among the most fundamental evolutionary quantities in common use, but what determines evolutionary rates has remained unclear. Here, we show…
Why highly expressed proteins evolve slowly
D. Allan Drummond, Jesse D. Bloom, Christoph Adami +2
Much recent work has explored molecular and population-genetic constraints on the rate of protein sequence evolution. The best predictor of evolutionary rate is expression level, f…
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins
D. Allan Drummond, Brent L. Iverson, George Georgiou +1
Recently, several groups have used error-prone polymerase chain reactions to construct mutant libraries containing up to 27 nucleotide mutations per gene on average, and reported a…