79 citations · 204 across the 3 of their papers we have counts for
4 papers · 1 filter
Thermodynamic and Kinetic Analysis of Sensitivity Amplification in Biological Signal Transduction
Hong Qian
Based on a thermodynamic analysis of the kinetic model for the protein phosphorylation-dephosphorylation cycle, we study the ATP (or GTP) energy utilization of this ubiquitous biol…
An Analysis of the Thermodynamics of Hydrophobic Solvation Based on Scaled Particle Theory
Hong Qian
A comprehensive, semi-quantitative model for the thermodynamics of hydrophobic solvation is presented. The model is based on a very simple premise suggested by the scaled particle…
From Discrete Protein Kinetics to Continuous Brownian Dynamics: A New Perspective
Hong Qian
An analysis on the discrete versus continuous views of kinetics of macromolecules is presented. It is shown that the discrete approach traditional to biochemistry is insufficient f…
Equations for Stochastic Macromolecular Mechanics of Single Proteins: Equilibrium Fluctuations, Transient Kinetics and Nonequilibrium Steady-State
Hong Qian
A modeling framework for the internal conformational dynamics and external mechanical movement of single biological macromolecules in aqueous solution at constant temperature is de…