79 citations · 204 across the 3 of their papers we have counts for
10 papers
Generalized Haldane Equation and Fluctuation Theorem in the Steady State Cycle Kinetics of Single Enzymes
Hong Qian, X. Sunney Xie
Enyzme kinetics are cyclic. We study a Markov renewal process model of single-enzyme turnover in nonequilibrium steady-state (NESS) with sustained concentrations for substrates and…
Entropy Production of Brownian Macromolecules with Inertia
Kyung Hyuk Kim, Hong Qian
We investigate the nonequilibrium steady-state thermodynamics of single Brownian macromolecules with inertia under feedback control in isothermal ambient fluid. With the control be…
Thermodynamic and Kinetic Analysis of Sensitivity Amplification in Biological Signal Transduction
Hong Qian
Based on a thermodynamic analysis of the kinetic model for the protein phosphorylation-dephosphorylation cycle, we study the ATP (or GTP) energy utilization of this ubiquitous biol…
Statistical Thermodynamics of General Minimal Diffusion Processes: Constuction, Invariant Density, Reversibility and Entropy Production
Hong Qian, Min Qian, Xiang Tang
The solution to nonlinear Fokker-Planck equation is constructed in terms of the minimal Markov semigroup generated by the equation. The semigroup is obtained by a purely functional…
Mesoscopic Nonequilibrium Thermodynamics of Single Macromolecules and Dynamic Entropy-Energy Compensation
Hong Qian
We introduce axiomatically a complete thermodynamic formalism for a single macromolecule, either with or without detailed balance, in an isothermal ambient fluid based on its stoch…
The Mathematical Theory of Molecular Motor Movement and Chemomechanical Energy Transduction
Hong Qian
The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Browni…