136 citations · 778 across the 45 of their papers we have counts for
4 papers · 1 filter
Network model of human aging: frailty limits and information measures
Spencer Farrell, Arnold Mitnitski, Kenneth Rockwood +1
Aging is associated with the accumulation of damage throughout a persons life. Individual health can be assessed by the Frailty Index (FI). The FI is calculated simply as the propo…
A model of autophagy size selectivity by receptor clustering on peroxisomes
Aidan I Brown, Andrew D Rutenberg
Selective autophagy must not only select the correct type of organelle, but also must discriminate between individual organelles of the same kind so that some but not all of the or…
Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils
Andrew D Rutenberg, Aidan I Brown, Laurent Kreplak
Collagen fibril cross-sectional radii show no systematic variation between the interior and the periphery of fibril bundles, indicating an effectively constant rate of collagen inc…
A dynamical network model for age-related health deficits and mortality
Swadhin Taneja, Arnold B. Mitnitski, Kenneth Rockwood +1
How long people live depends on their health, and how it changes with age. Individual health can be tracked by the accumulation of age-related health deficits. The fraction of age-…