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physics.med-ph2026

Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement

Jalaj Maheshwari, Wensi Wu, Christopher N. Zelonis +9

Finite element (FE) simulations emulating transcatheter pulmonary valve (TPV) system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properti…

physics.med-ph2025

Simulation of Repair on Dynamic Patient-Specific Left Atrioventricular Valve Models

Stephen Ching, Christopher Zelonis, Christian Herz +12

Purpose: To develop and evaluate a dynamic, image-derived patient-specific physical simulation platform for the assessment of left atrioventricular valve (LAVV) repair strategies i…

physics.med-ph2025

Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework

Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8

Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…

physics.med-ph2025

Geodesic-based Predictive Shape Modeling of the Right Ventricle in Patients with Hypoplastic Left Heart Syndrome

Ye Han, James Fishbaugh, Jared Vicory +9

Hypoplastic left heart syndrome (HLHS) is characterized by severe underdevelopment of left ventricle requiring staged surgical reconstruction (stages) to allow the right ventricle…

physics.med-ph2024

Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure

Nicolas R. Mangine, Devin W. Laurence, Patricia M. Sabin +9

Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae ten…

physics.med-ph2024

FEBio FINESSE: An open-source finite element simulation approach to estimate in vivo heart valve strains using shape enforcement

Devin W. Laurence, Patricia M. Sabin, Analise M. Sulentic +4

Finite element simulations are an enticing tool to evaluate heart valve function in healthy and diseased patients; however, patient-specific simulations derived from 3D echocardiog…