8 papers
An open-source computational framework for immersed fluid-structure interaction modeling using FEBio and MFEM
Ryan T. Black, Steve A. Maas, Wensi Wu +4
Fluid-structure interaction (FSI) simulation of biological systems presents significant computational challenges, particularly for applications involving large structural deformati…
Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement
Jalaj Maheshwari, Wensi Wu, Christopher N. Zelonis +9
Finite element (FE) simulations emulating transcatheter pulmonary valve (TPV) system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properti…
Integrated Open-Source Framework for Simulation of Transcatheter Pulmonary Valves in Native Right Ventricular Outflow Tracts
Christopher N. Zelonis, Jalaj Maheshwari, Wensi Wu +14
Background - Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF), leading to late morbidity and mortality. Transcatheter native outfl…
Simulation of Repair on Dynamic Patient-Specific Left Atrioventricular Valve Models
Stephen Ching, Christopher Zelonis, Christian Herz +12
Purpose: To develop and evaluate a dynamic, image-derived patient-specific physical simulation platform for the assessment of left atrioventricular valve (LAVV) repair strategies i…
Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework
Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8
Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…
Geodesic-based Predictive Shape Modeling of the Right Ventricle in Patients with Hypoplastic Left Heart Syndrome
Ye Han, James Fishbaugh, Jared Vicory +9
Hypoplastic left heart syndrome (HLHS) is characterized by severe underdevelopment of left ventricle requiring staged surgical reconstruction (stages) to allow the right ventricle…