110 citations · 543 across the 33 of their papers we have counts for
38 papers
PolyHoop: Soft particle and tissue dynamics with topological transitions
Roman Vetter, Steve V. M. Runser, Dagmar Iber
We present PolyHoop, a lightweight standalone C++ implementation of a mechanical model to simulate the dynamics of soft particles and cellular tissues in two dimensions. With only…
Organ-specific Branching Morphogenesis
Christine Lang, Lisa Conrad, Dagmar Iber
A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morph…
The Control of Lung Branching Morphogenesis
Dagmar Iber
Branching morphogenesis generates epithelial trees which facilitate gas exchange, filtering, as well as secretion processes with their large surface to volume ratio. In this review…
Global optimization using Gaussian Processes to estimate biological parameters from image data
Diana Barac, Michael D. Multerer, Dagmar Iber
Parameter estimation is a major challenge in computational modeling of biological processes. This is especially the case in image-based modeling where the inherently quantitative o…
Simulation of morphogen and tissue dynamics
M. D. Peters, L. D. Wittwer, A. Stopka +3
Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into deve…
Simulating Organogenesis in COMSOL: Tissue Mechanics
M. D. Peters, D. Iber
During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and…