1 citations · 1 across the 16 of their papers we have counts for
24 papers
Instantaneous arithmetic computation via ratio-encoding in chemical reaction networks
David F. Anderson, Badal Joshi
We develop a general framework for instantaneous arithmetic computation using chemical reaction networks. Numerical values are encoded by ratios of species concentrations: an exten…
Bistability, Absolute Concentration Robustness, and Hysteresis in Dual-Site Futile Cycles with Bifunctional Enzymes
Badal Joshi, Tung D. Nguyen, Matthew D. Johnston
Bifunctional enzymes, which catalyze both the forward and reverse steps of a substrate modification reaction, arise naturally in bacterial two-component signaling systems and metab…
Computing with reaction networks at input-independent speed: exponential and logarithmic functions
David F. Anderson, Badal Joshi, Tung D. Nguyen
The concept of \textit{input-independent computational speed} for chemistry-based analog computers was introduced in Anderson-Joshi (2025), where it was shown that arithmetic opera…
Bifunctional enzyme action as a source of robustness in biochemical reaction networks: a novel hypergraph approach
Badal Joshi, Tung D. Nguyen
Substrate modification networks are ubiquitous in living, biochemical systems. A higher-level hypergraph "skeleton" captures key information about which substrates are transformed…
Chemical mass-action systems as analog computers: implementing arithmetic computations at specified speed
David F. Anderson, Badal Joshi
Recent technological advances allow us to view chemical mass-action systems as analog computers. In this context, the inputs to a computation are encoded as initial values of certa…
Bifunctional enzyme provides absolute concentration robustness in multisite covalent modification networks
Badal Joshi, Tung D. Nguyen
Biochemical covalent modification networks exhibit a remarkable suite of steady state and dynamical properties such as multistationarity, oscillations, ultrasensitivity and absolut…